Abstract Title:

Antifungal Activity of Ethanol-extracted(L) (Achiote) on, at Six Different Concentrations.

Abstract Source:

J Contemp Dent Pract. 2019 Oct 1 ;20(10):1159-1163. Epub 2019 Oct 1. PMID: 31883250

Abstract Author(s):

Lucia Poma-Castillo, María Espinoza-Poma, Franco Mauricio, Cesar Mauricio-Vilchez, Daniel Alvítez-Temoche, Frank Mayta-Tovalino

Article Affiliation:

Lucia Poma-Castillo


AIM: The aim of the study was to determine the antifungal activity of six different concentrations of the ethanol extract of(L) (Achiote) on the strains of(ATCC 90028).

MATERIALS AND METHODS: The ethanol extract of(L) (BEE) was prepared in six different concentrations (5%, 10%, 20%, 40%, 60%, and 100%), which were confronted with the positive control group (Nystatin 100,000 UI/mL). The total sample consisted of= 174 wells inoculated with each concentration evaluated in the Petri dishes. The cultivation procedure was carried out at a temperature of 37°C, and then the 6 mm diameter wells on which the sowing of thein suspension was carried out. Subsequently, the BEE (Achiote) was inoculated in all the concentrations mentioned in the same way for Nystatin; finally, the inhibition halos were evaluated by the Kirby-Bauer method at the scheduled times of 24, 48, and 72 hours.

RESULTS: The highest antifungal activity was found at 24 hours and this increased directly proportional to the concentration of BEE (5%, 10%, 20%, 40%, 60%, and 100%): 11± 0, 11 ± 0, 13.1 ± 1.3, 17.2 ± 0.8, 19.1 ± 1.0, and 21.4 ± 1.3 mm, respectively. However, there was no statistically significant difference when compared with Nystatin, at>0.05 Conclusion: It was shown that 5%, 10%, 20%, 40%, 60%, and 100% BEE had an antifungal effect against. However, there were no statistically significant differences against the effect of Nystatin at 100,000 IU/mL, who has an inhibitory effect greater than BEE, with a significance level of<0.05.

CLINICAL SIGNIFICANCE: This article describes the antifungal activity and the possible impact on dentistry that the use of(L) may have because according to our results it had an antifungal effect against strains of. This opens a great line of research to potentially use this natural resource in dentistry. How to cite this article: Poma-Castillo L, Espinoza-Poma M, Mauricio F,Antifungal Activity of Ethanol-extracted(L) (Achiote) on, at Six Different Concentrations. J Contemp Dent Pract 2019;20(10):1159-1163.

Study Type : In Vitro Study
Additional Links
Diseases : Candida Albicans
Pharmacological Actions : Antifungal Agents : CK(494) : AC(306)

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