Uveitis responding on gluten free diet in a girl with celiac disease and diabetes mellitus type 1.
Gastroenterol Clin Biol. 2010 Apr-May;34(4-5):319-20. Epub 2010 Apr 28. PMID: 20427138
Department of Ophtalmology, Farhat Hached Hospital, Sousse, Tunisia.
A 9-year old girl with a history of diabetes mellitus type 1, presented with visual loss of the left eye. The right eye examination was unremarkable. Slit-lamp examination revealed few small and fine keratic precipitates. We noted 2+ flare in the vitreous. There was no choroiditis, papillitis or retinal vasculitis. No aetiology was found. The patient was treated by topical and systemic corticosteroids without any improvement. Celiac disease was discovered by the presence of celiac antibodies in the work-up of joint pain and diabetes mellitus type 1. Antiendomysium antibodies and anti-transglutaminase antibodies were both positive. A small bowel biopsy confirmed celiac disease. A gluten free diet was set up and corticosteroids were tapered off. Recovery of the uveitis was obvious during gluten free diet and normalized within two months.