[Topical ozone application: An innovative therapy for infantile atopic dermatitis].
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28 ;43(2):163-167. PMID: 29559600
To evaluate the clinical efficacy and safety of the innovative topical ozone therapy for infantile atopic dermatitis. Methods: Sixty children with atopic dermatitis were divided into a treatment group and a control group. The treatment group was showered with ozonated water (3-5 times a week) and smeared with ozonated oil (twice a day), while the control group was washed with warm running water and smeared withbase oil, adding moisturizer if necessary. The treatment course was 2 weeks. Efficacy and side effect were evaluated. Results: The skin exudation was reduced and erosion was healing after 3-5 days topical ozone therapy for infantile atopic dermatitis. The effective rates were 80.0% and 20.0% inthe treatment group and control group for 1 week, and 89.6% and 30.7% for 2 weeks, respectively, with significant difference between the 2 groups (P<0. 001). Conclusion: Innovative treatment of infantile atopic dermatitis with topical ozone application is safe and effective, which is worth popularizing in clinic.