Article Publish Status: FREE
Abstract Title:

The efficacy of Nigella sativa supplementation for asthma control: a meta-analysis of randomized controlled studies.

Abstract Source:

Postepy Dermatol Alergol. 2021 Aug ;38(4):561-565. Epub 2020 Feb 24. PMID: 34658694

Abstract Author(s):

Anqiang Han, Danqin Shi

Article Affiliation:

Anqiang Han


Introduction: The efficacy of Nigella sativa supplementation for asthma control remains controversial. We have conducted a systematic review and meta-analysis to explore the influence of Nigella sativa supplementation on asthma control.

Material and methods: We have searched PubMed, EMBASE, Web of science, EBSCO, and Cochrane library databases through June 2019 for randomized controlled trials (RCTs) assessing the efficacy of Nigella sativa supplementation for asthma control.

Results: Four RCTs are included in the meta-analysis. Overall, compared with the control group for asthma, Nigella sativa supplementation is associated with the increased ACT scores (SMD = 0.50; 95% CI: 0.11-0.88;= 0.01), and FEV1 (SMD = 1.84; 95% CI: 0.07-3.60;= 0.04), but demonstrates no obvious impact on PEF (SMD = 3.11; 95% CI: -1.30 to 7.52;= 0.17), IL-4 (SMD = -0.31; 95% CI: -1.21 to 0.59;= 0.50), or IFN-γ (SMD = 1.11; 95% CI: -0.44 to 2.67;= 0.16).

Conclusions: Nigella sativa supplementation may provide additional benefits for the treatment of asthma.

Study Type : Meta Analysis

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Sayer Ji
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