Article Publish Status: FREE
Abstract Title:

Effects of Ashwagandha () on VO: A Systematic Review and Meta-Analysis.

Abstract Source:

Nutrients. 2020 Apr 17 ;12(4). Epub 2020 Apr 17. PMID: 32316411

Abstract Author(s):

Jorge Pérez-Gómez, Santos Villafaina, José Carmelo Adsuar, Eugenio Merellano-Navarro, Daniel Collado-Mateo

Article Affiliation:

Jorge Pérez-Gómez


The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha () on maximum oxygen consumption (VO), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VOdata, with means± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VOin healthy adults and athletes (= 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VOin athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high.

Study Type : Meta Analysis, Review

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