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Abstract Title:

The meaning of aluminium exposure on human health and aluminium-related diseases.

Abstract Source:

Biomol Concepts. 2013 Feb ;4(1):77-87. PMID: 25436567

Abstract Author(s):

Guido Crisponi, Daniela Fanni, Clara Gerosa, Sonia Nemolato, Valeria M Nurchi, Miriam Crespo-Alonso, Joanna I Lachowicz, Gavino Faa

Article Affiliation:

Guido Crisponi

Abstract:

The aim of this review is to attempt to answer extremely important questions related to aluminium-related diseases. Starting from an overview on the main sources of aluminium exposure in everyday life, the principal aspects of aluminium metabolism in humans have been taken into consideration in an attempt to enlighten the main metabolic pathways utilised by trivalent metal ions in different organs. The second part of this review is focused on the available evidence concerning the pathogenetic consequences of aluminium overload in human health, with particular attention to its putative role in bone and neurodegenerative human diseases.

Study Type : Review

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