Article Publish Status: FREE
Abstract Title:

Weight reduction improves immune system and inflammatory cytokines in obese asthmatic patients.

Abstract Source:

Afr Health Sci. 2020 Jun ;20(2):897-902. PMID: 33163057

Abstract Author(s):

Fadwah M Al-Sharif, Shehab M Abd El-Kader, Ziyad A Neamatallah, Afnan M AlKhateeb

Article Affiliation:

Fadwah M Al-Sharif


Background: Activation of immunological and systemic inflammation markers are common in obesity and asthma.

Objective: The target of this study was to assess impact of weight reduction on immunological and systemic inflammation markers in obese asthma patients.

Material and methods: Eighty asthmatic patients of both sex; their age and body mass index (BMI) mean were 38.72± 7.14 year and 32.65 ± 3.18 Kg/m2 respectively. Exclusion criteria included smokers, infections, vaccinations, cancer, surgery, immune system disorders and medications that may influence immune system function as anti-inflammatory medications, analgesics and anti-depressant. All subjects were randomly enrolled in weight reduction group (group A) or control group (group B).

Results: The main findings in the present study indicated that weight reducing program in group (A) was associated with significant reduction in the mean values of IL6, TNF-α, and IL8 in addition to significant increase in the mean values of CD4 and CD8 cell count . However, findings of group (B) showed no significant changes. Moreover, Comparison between both groups at the end of the study revealed significant differences.

Conclusion: Weight reduction improved immunological and systemic inflammation markers in obese asthma patients.

Print Options

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.